By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1)
These questions arise in part from social-media-driven interest in the compound and in part from what limited early data exist
It has been used to treat neurological diseases such as Huntingtons chorea, Tourettes disease, cerebellar ataxia and certain types of seizures
What Are LipoVite Injections
Users and researchers note that AOD 9604 is primarily valued for its role in promoting fat metabolism and its favorable safety profile compared to full HGH treatments
Some studies suggest the quinolinium structure is sufficiently NNMT-selective that it should not broadly deplete SAM, but the wider metabolic picture remains an active research consideration