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Difficult timing: John explains that oral semaglutide must be taken on an empty stomach and requires a 30-minute wait before eating, which can be hard to maintain long-term
A higher likelihood of loose stools or diarrhea
Board member Dr
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The primary endpoints were changes in HbA1c and body weight ( 4.2 SURPASS-2 trial comparison of tirzepatide and semaglutide The SURPASS-2 trial, comprising 1,879 patients with type 2 diabetes, compared once-weekly tirzepatide (5 mg, 10 mg, 15 mg) with semaglutide 1 mg over a 40-week period
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