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At night, rising melatonin acts on MT1/MT2 receptors in various tissues to induce nighttime physiology: it promotes the onset of sleep, lowers core body temperature, slows gastrointestinal activity, and modulates metabolism to a nocturnal state

Because the mechanism is appetite-based rather than metabolically suppressive, it tends to reduce intake without sapping energy

Although grade 3 and 4 toxicities could be managed, they led to dose interruption and reduction (NCT03579316)

often its not

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The reason to show it long-hand rather than just stating the answer is that on the 10 mg vial the draw is tiny, and a reader who understands the chain can catch an error the moment a number looks wrong