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The rate-limiting step involves glutamate-cysteine ligase catalyzing the formation of -glutamylcysteine from L-glutamate and L-cysteine, followed by glutathione synthetase adding glycine to form the complete tripeptide

Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis