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Acknowledgements This work was supported by the National Natural Science Foundation of China (82272660, 82160456, and 81972399), the Guizhou Provincial Science and Technology Projects (ZK[2022]394), the Excellent Young Talents Plan of Guizhou Medical University ([2020]47), the Natural Science Foundation Research Team of Guangdong Province (2018B030312001), the Plan on Enhancing Scientific Research in GMU (02-410-2302289XM), the Basic and Applied Basic Research Project of the Guangzhou Basic Research Program (202201011411)
The negative correlations between C4A and C4B, as well as between C4L and C4S copy numbers, more likely indicate that these loci reside at opposing ends of a risk (C4A and C4L) and protective (C4B and C4S) spectrum, existing in a state of linkage disequilibrium (143)
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