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A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors

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Common side effects include: Nausea GI discomfort Fatigue during dose escalation Any serious adverse events in cardiovascular outcome trials were comparable to placebo

5-amino-1-methylquinolinium has been found to reduce adipocyte size and lower plasma total cholesterol levels in diet-induced obese mice and improve muscle strength in aged mice 204,205 (Fig