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Despite promising preclinical results, the application of antioxidant therapies in clinical settings has faced challenges due to inconsistent outcomes, highlighting the need for targeted approaches
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A recent overview on the biological and pharmacological activities of ferulic acid
This reduces the need to "mega-dose" and significantly lowers the risk of the digestive upset associated with high-dose, poorly absorbed powders
More recently, it has also been reported that several cell types and tissues show different non-genomic responses (Molina et al., 2017, 2018)
These pharmacokinetic differences inform the trade-offs in onset, convenience, and dosing convenience
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