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For more than 100 million years, evolution has fine-tuned venoms in snakes, lizards, fish, scorpions, and a cornucopia of other creatures into tactical weapons
GLP-1 receptor agonist medications are typically considered for type 2 diabetes when other treatments are ineffective or inappropriate, particularly if you have a BMI 35 kg/m with weight-related complications
People with T2DM and obesity have varying presentations with differing metabolic and organ involvement, so GLP1 plus treatments might offer differential advantages, depending on the clinical picture
Gastrointestinal intolerance, particularly nausea and vomiting, may affect adherence despite their tendency to diminish over time (Nunn et al., 2024)
Regular check-ups are key during this time
The cost difference between Rybelsus and Januvia raises legitimate questions about cost-effectiveness for adults with type 2 diabetes who have modest glycemic targets
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