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Among more than 17,000 patients with preexisting cardiovascular disease, who are overweight or obese and do not have diabetes, those who took semaglutide showed a 20 percent reduction in major adverse cardiovascular events and nonfatal strokes

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When you stop, appetite returns to baseline and weight regain is common, typically 50 to 70 percent of lost weight over the following year without intervention

J Clin Endocrinol Metab 86:38533860 Lugari R, Dei Cas A, Ugolotti D et al (2002) Evidence for early impairment of glucagon-like peptide 1-induced insulin secretion in human type 2 (non insulin-dependent) diabetes

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