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Surprisingly, a daily activation of GPR119 with OEA or other synthetic agonists, increases -cell responsiveness in islets transplanted into STZ-induced diabetic mice (328)
Not drinking enough water can worsen the side effects, too
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Slower Titration to Reduce Side Effects Increasing doses too quickly can lead to more severe side effects such as nausea, vomiting, dehydration, and even discontinuation of treatment
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