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Tirzepatide is a dual incretin receptor agonist, meaning it activates both the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor
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Similarly, semaglutide has been shown to affect periods through the same insulin-mediated mechanism, though tirzepatide dual-receptor action may produce faster or more pronounced changes
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Glucagon-like peptide-1 receptor agonists and hepatic decompensation events in patients with cirrhosis and diabetes
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