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We built two baskets of leading drugmakers: one focused on GLP-1 producers (Novo Nordisk, Eli Lilly, Sanofi, Teva and Hikma), and another on non-GLP-1 peers (Novartis, Johnson & Johnson, GlaxoSmithKline, AbbVie and Bayer)

4.8% (similar between groups) Discontinuation Due to AEs: 12% (CagriSema) vs

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Methods to measure the physiological forward reaction have also been developed

Side effects: Most initial side effects have subsided

However, optimization of antigen targets, along with exploration of new linker, antibody, and payload technologies, holds promise in amplifying the benefit of the next generation of ADCs (Fig