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The dysregulation of SETD2-mediated H3K36 methylation, mainly through its failure to effectively regulate transcription and repair DNA damage, can lead to neuronal dysfunction and contribute to neurodegenerative processes (Pappas and Rabin, 1993
CPT Pharmacometrics Syst Pharmacol 2024;13:494503: 10.1002/psp4.13099
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