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A double-blind, randomized, placebo-controlled trial employing 227 adults with chronic kidney diseases were taking 25 mg, 75 mg, or 150 mg of bardoxolone methyl every day for a period of 24 weeks or 52 weeks

Phenotypic outcomessuch as improved insulin sensitivity or enhanced thermogenesismay provide more robust translational anchors than circulating peptide levels alone

10.1016/j.medidd.2023.100165 Med Drug Discov

The opinions expressed are those of the author and are based on publicly available information believed to be reliable at the time of writing

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For routine monitoring , inform your healthcare team at regular appointments about any abdominal symptoms, even if mild or intermittent