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NFT pretreatment resulted in a marked shift of LD 50 toward higher concentrations of either NFT or paraquat required for the induction of cell damage compared to cells without pretreatment
Furthermore, the integration of temporal and spatial omics profiling may enable dynamic monitoring of signaling rewiring, informing the design of context specific, resistance-preemptive regimens
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Our findings open up the possibility that upregulated glycolysis, among other benefits, might provide an increased FBP supply for Rac1 activation, promoting endothelial sprouting and immune cell migration