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To reduce potential confounding effects in the comparison between patients who received semaglutide and those who received dulaglutide, we estimated a propensity score (PS) using a logistic regression model adjusted for all covariates

The medication continues to improve insulin sensitivity, which can protect against the risk of developing diabetes or heart disease in the long run

This occurs because semaglutide slows gastric emptying as part of its mechanism of action, which can lead to harder, less frequent stools

Age over 65 Older adults have higher rates of nausea and vomiting on GLP-1 agonists, possibly due to age-related changes in gastric motility

Golden DB, Moffitt J, Nicklas RA, et al

Intermediate effect sizes are considered biologically meaningful because average proportions of variance explained in physiological, ecological and evolutionary studies are usually below 7% 32