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A practical severity estimate based on the available preclinical signals: Serotonergic risk : Low-to-moderate plausibility based on rodent monoamine modulation data, but direction of effect (agonism vs

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Damage to the epithelial cells lining the stomach stops the production of intrinsic factor

In a recent study, inhibition of TH by low-dose -MT initiated at the early stage was able to prevent LRRK2 G2019S mutation-induced DA neurodegeneration in in vivo PD models [44, 164]

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