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Description

We demonstrate that this effect of a GLP-1R agonist was translationally relevant in human islets through application of a single-cell RNA-Seq (scRNA-Seq) technology, droplet-assisted RNA targeting by single-cell sequencing (DART-Seq) (23), a high-sensitivity scRNA-Seq approach

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Immunofluorescence imaging revealed that FITC-labeled exendin 939 was bound to TRPV1 on the cell surface in CHO K1 cells expressing human TRPV1 but not in nave CHO K1 cells (Fig

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