The most common reason cause of the Jarisch-Herxheimer Reaction are taking high doses of antifungals or antibiotics, but the condition can also occur when rapid changes of diet cause large-scale die-off of gut microflora overgrowth (also see: SIBO Diet)
However, STAT3 inhibits the cellular inflammatory response and promotes cell survival (Ramkumar et al., 2021)
However, excessive exercise and overtraining can have adverse effects, so it's important to follow a balanced exercise program
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Give it a few weeks and discuss any changes (or lack thereof) with your healthcare provider at follow-up