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After first puncture: the familiar 28 days does not come from the bacteriostatic water label, which contains no discard-after-entry statement at all

Tracking the 28-day clock across them is the most-documented multi-bottle workflow: Label each bottle on first puncture with a date written on the bottle itself or on tape applied to the bottle

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Practical takeaway: Physical rejuvenation in mice is encouraging but must be interpreted cautiously

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doi: 10.1111/(ISSN)1438-8677 9 Clemente-MorenoM