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Similarly, microdose scheduling can help maintain therapeutic effect while minimizing the peaks and troughs that contribute to both side effects and tolerance development

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Your choice should balance two competing needs: measurable volumes for your smallest planned dose, and single-draw capability for your largest planned dose

When taking semaglutide, you must let your anaesthetist or endoscopist know if you are using this medication, as it may affect fasting status and risk of aspiration during the procedure

Canada's regulatory framework allows generic manufacturers to begin preparing ANDA-equivalent submissions up to 2 years before patent expiration, meaning generic semaglutide could launch in Canada as early as 2029

However, the absence of MS-specific contraindications does not eliminate the need for careful clinical assessment when initiating semaglutide in MS patients