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In DN, persistent hyperglycemia is known to augment OS, thereby contributing to nerve damage and dysfunction

Then, researchers discovered they have a powerful ability to help people shed unwanted pounds, as a weight loss medication, too

This dual strategy is increasingly recommended by cardiologists and endocrinologists managing high-risk patients

While Raibick said her initial use of semaglutide helped her gain the confidence she needed to hit the gym and adjust her diet, she was worried about titrating, or weaning off of the drug, and subsequently gaining back the weight shes lost

Phenotypic expression is variable and typically requires additional metabolic stressors such as obesity, insulin resistance, hypothyroidism, or hormonal changes

PMID 27315480