"Berberine alongside a GLP-1 can have a compounding effect on lowering blood sugar, which can lead to hypoglycemia," says Grace Engels, RD, of Grace Engels Nutrition
A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication
doi:10.1210/jcem.87.4.8421 Zheng H, Wei J, Wang L, et al
Creatine does not add to this risk, but adequate hydration becomes even more important when combining both
Ensure you are getting enough protein and essential minerals
Exposure to cold temperatures activates production of proteins including RNA-binding motif protein 3 (RBM3), which demonstrates neuroprotective effects and may help maintain muscle mass during periods of reduced activity