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Potential mechanism: By inhibiting the expression of myostatin, negative regulation of muscle growth can be relieved.Diabetes foot ulcer: local application of IGF-1 LR3 gel (0.1 mg/cm ) can accelerate wound closure, and its mechanisms include:Stimulate fibroblast migration and collagen synthesis.Promote the secretion of vascular endothelial growth factor (VEGF) and improve local blood supply
While the fatty acid profile is similar across these forms, there are some differences in terms of processing and additional constituents (Dayrit 2014)
GH accelerates collagen turnover and promotes repair of tendons and ligaments (Doessing et al., Growth Hormone & IGF Research )
Additional important metabolic regulatory enzymes that require flavin as a co-factor include, succinate dehydrogenase (TCA cycle and complex II of oxidative phosphorylation), glycerol-3-phosphate dehydrogenase (involved in the glycerol phosphate shuttle and triglyceride synthesis), and xanthine oxidase involved in purine nucleotide catabolism
Mechanistic descriptions of each component cite peer-reviewed primary literature and reviews indexed in PubMed
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