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METHODS All animal procedures were approved by the Institutional Animal Care and Use Committee of the Pusan National University Hospital (approval number: PNUH-2019-157)
During perimenopause, when your DAO enzyme is already less effective at clearing histamine (because of fluctuating oestrogen), adding a high-histamine drink tips the balance
This is because alcohol increases the concentration of CYP2E1 in liver cells, causing APAP to be oxidized faster
May 1997;27(5):387-391
However, it also comes with serious safety concerns, and should only be used in medical settings
It might not be your lifestyle
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