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Topical copper peptide and skin: Mechanisms and clinical applications

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Understanding how AHK-Cu fits among other options helps researchers make informed protocol decisions

doi: 10.1111/j.1600-6143.2010.03126.x 174

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Research has demonstrated that GLP-1RAs significantly inhibit the expression of MMP-2 and MMP-9 in the human ovarian cancer cell line SKOV-3 within a TNF--induced inflammatory microenvironment, while simultaneously upregulating the levels of their inhibitors, tissue inhibitors-1 (TIMP-1) and tissue inhibitors-2 (TIMP-2) [78, 87]