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In the present review, we describe homocysteine metabolism and its regulation by tissue folate and S-adenosylmethionine levels
(2022, October 2)
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Notably, the ongoing phase I/II trial of XNW5004, an EZH2 inhibitor, in combination with pembrolizumab (NCT06022757) exemplifies the effort to reprogram epigenetic states and restore ICB sensitivity in solid tumors resistant to conventional treatments
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