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Most published topical studies have used concentrations between 1 percent and 3 percent

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In hypothyroidism, slowed gut motility can intensify these issues

( a , b ) Cumulative distribution plot of observed percentage change from baseline over time in body weight for participants in the full analysis set during the in-trial observation period* (a) and on-treatment observation period (b)

Participants will be required to be receiving weekly subcutaneous semaglutide at a minimum dose of 1 mg, to have achieved at least 10% weight reduction from pre-treatment body weight, and to have demonstrated stable weight over the preceding 12 weeks

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