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Another study explored the potential interaction between GHK-Cu and hyaluronic acid (HA) on collagen synthesis, particularly focusing on their potential collaborative actions in dermal fibroblasts and an ex-vivo skin model

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Future research integrating multi-omics approaches, such as metagenomics, metabolomics, and host transcriptomics, together with large-scale longitudinal studies and well-designed clinical trials, will be essential to clarify causal mechanisms and evaluate the long-term efficacy of microbiome-targeted interventions