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Cranial cruciate ligament (CCL) disease the canine equivalent of a human ACL tear is among the most common orthopedic conditions, especially in medium and large breeds
Patients should not use instructions from online forums or attempt to calculate injection volume without verifying the product concentration
Despite that, a hidden market of practitioners administering these products has flourished anyway
Some people report improved skin firmness
Most practitioners recommend starting at 250-300 mcg daily to assess tolerance, then potentially increasing to 400-500 mcg if initial response is suboptimal and no side effects occur
Presented for research literature review only Peters WH et al
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