doi:10.1186/1475-2891-14-6 [PubMed] Lehotsk J, Tothov B, Kovalsk M, et al

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doi:10.3390/jcm10091891
However, while technical limitations may exist regarding adequate GSH rescue, we cannot rule out non-canonical and non-enzymatic functions of GCLC contributing to lipid-related phenotypes
One significant concern is the potential for treatment discontinuation due to cost, drug shortage, or adverse effects, which can lead to a deterioration in key cardiometabolic parameters, including glycemic control, blood pressure, and cholesterol levels
Hepatology 70 , 682695 (2019)