May support healthy metabolic processes including fat metabolism, energy expenditure, and body composition when combined with proper lifestyle factors
Preclinical research suggests NNMT inhibition may affect fat cell metabolism, insulin sensitivity, body weight, and energy expenditure in animal or cell models
Metformin may result in suboptimal oral vitamin B12 absorption by competitively blocking the calcium-dependent binding of the intrinsic factor-vitamin B12 complex to its receptor
By preserving NAD+ levels, it supports mitochondrial health within muscle cells, which is essential for energy production and repair
Stubborn fat that does not respond to diet and exercise is often a metabolic problem, not a willpower problem
To assess the role of 3-AR in mediating these effects, researchers examined AOD9604 and hGH treatment in 3-KO mice