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For targets with no existing fluorophore conjugated antibody the following primary antibodies were used: anti NRF2 polyclonal (1:200, Thermofisher, PA5-27882)

However, several studies have also shown that chronic treatment with AOD-9604 had no adverse effect on insulin sensitivity of researched animals

The use of proton pump inhibitors (PPIs) has been associated with an increased risk of vitamin B12 deficiency, particular in older adults and those on long-term PPI therapy. Nutrition Reviews Duration-Dependent Risk Assessment The risk of B12 deficiency from PPIs grows with time

It is conceivable that the discovery of more molecular scaffolds with such self-recognizing properties could open up new possibilities in prodrug design and beyond

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