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Adult male C57BL/6 mice on a 60% kcal-from-fat high-fat diet received intraperitoneal or oral 5-Amino-1MQ at amounts in the milligram-per-kilogram range or vehicle, over an 11-day treatment period in the published protocol

This oncologic safety concern is magnified by the fact that many cancers remain clinically silent during their early developmental stages

Liver X receptor mediates hepatic triglyceride accumulation through upregulation of G0/G1 switch gene 2 expression

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levels influence metabolic health, stress response, and tissue regeneration 1,3

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