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In TRIUMPH-1, people taking retatrutide 12mg lost an average of 28.3% of their starting body weight at 80 weeks
But with all that information out there, it can be hard to find out who it's for and how to get it
Yildiz O, Ulusoy KG
TRANSCEND-T2D-1 (Type 2 Diabetes): Results released in March 2026 found that participants with type 2 diabetes who received the 12 mg dose lost an average of 16.8% of their body weight after 40 weeks
Key Findings: Asian participants: 21.3% mean weight loss with CagriSema (similar to overall population) Safety profile consistent across ethnicities GI tolerability similar but potentially lower discontinuation rates in Asian populations Clinical Significance: Supports global applicability of cagrilintide-based therapies across diverse populations
Celebrities and influencers such as Oprah Winfrey, Elon Musk and Rachael Knight Guellete are confirmed to be using GLP-1s and will often be seen promoting these products
