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Genome instability in cancer cells promotes the accumulation of cytoplasmic DNA species, including micronuclei, which activate the cGASSTING pathway and drive the expression of pro-inflammatory cytokines and type I interferons, thereby stimulating immune cells and enhancing antigen presentation within the tumor microenvironment 65,66

6.2.1 TCTP-PTD variants We investigated nasal exendin-4 delivery by several TCTP-PTD variants and their hypoglycemic responses in normal rats and in diabetic mice, respectively

Ethics statement The animal protocol was specifically approved by the Scientific Ethics Committee of Ethics Committee of the School of Public Health, Jilin University (approval No

doi:10.1007/s13181-013-0374-z