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Blood Sugar Effects Both medications improve glucose metabolism: Liraglutide: HbA1c reduction of 0.5-1.0% at weight loss doses Originally developed for diabetes (Victoza) Modest glucose benefits at Saxenda doses Semaglutide: HbA1c reduction of 1.0-1.8% at diabetes doses Greater glucose improvement than liraglutide Significant benefit for prediabetes and diabetes For patients with diabetes or prediabetes, semaglutide provides greater metabolic benefit

For short-term storage, a refrigerator is perfectly acceptable

Claudia Fox, MD, MPH , co-director of the Center for Pediatric Obesity Medicine at University of Minnesota Medical School, said the level of BMI reduction in the semaglutide group was close to that seen with bariatric surgery

At higher concentrations, going above 50 units means very high milligram doses