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Also, side effects from these medications are typically mild

The authors hypothesized that the medication may trigger immune responses, as the inflammation resolved after intralesional hyaluronidase administration

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Its binding to VMAT2 is very strong, making it's effect appear irreversible, with trace amounts of the drug remaining bound to vesicular membranes for many days, and its clinical effects lasting many days to weeks, and may persist until new transporter proteins are synthesized (German et al, 2015