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Why is Novo Nordisk struggling if they make billions on Ozempic

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Using a 10% or more increase in whole body oxygen con-sumption as their endpoint, 13 patients who received NAC were considered responders, and 16 were considered nonresponders

Secondary objectives were assessment of the effect of NMP on post-transplant clinical outcomes and ischaemia-reperfusion injury, identification of predictive biomarkers, and characterisation of the performance of the preservation system

This helps explain part of the CagriSema vs retatrutide research gap

Lower blood pressure reduces strain on your heart and blood vessels (Heart, 2024)