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The body struggles to reduce dehydroascorbate (oxidised vitamin C) without enough glutathione
This cascade-responsive system maximizes tumor selectivity by requiring sequential satisfaction of multiple tumor-specific conditions, achieving strong anticancer efficacy with minimal systemic toxicity, particularly valuable in receptor-negative triple-negative breast cancer where ligand-based targeting is not feasible [182]
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Immunological risks : As a foreign synthetic peptide, it could theoretically provoke immune responses or allergic reactions
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This formulation utilizes Intravail technology utilizing n-dodecyl--D-maltoside (DDM) to temporarily loosen intercellular mucosal junctions, facilitating rapid systemic absorption of epinephrine even through congested nasal passages (Howell, 2024
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