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Ketterer B, Coles B, Meyer DJ
Efficacy of daily low-dose sildenafil for treating interstitial cystitis: results of a randomized, double-blind, placebo-controlled trial treatment of interstitial cystitis/painful bladder syndrome with low-dose sildenafil
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In these cases, high B12 is not causing the liver damage
Animal Evidence (Moderate) Uno and Kubo (1992) evaluated peptide-copper complexes in C3H mice a standard model for hair growth research
however, some individuals may experience mild skin sensitivity depending on: Formulation concentration Skin type Frequency of cosmetic application Concurrent cosmetic ingredients Possible Cosmetic Reactions Mild redness Temporary tingling sensations Skin irritation Dryness Increased skin sensitivity Temporary blue discoloration when higher concentrations are utilized Higher concentrations are not always preferred and may increase the likelihood of cosmetic skin irritation, particularly in sensitive-skin formulations
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