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The mechanistic comparison is particularly interesting: CagriSema adds amylin signaling to GLP-1, while retatrutide adds glucagon and GIP signaling

Translating a 15 mg/kg murine dose directly to humans underscores a severe translational gap in the source paper

Finally, we note that severe oxidative stress causes a "methyl trap" such that the model concentration of 5mTHF more than doubles

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3776-C TRENDS IN ORAL MEDICATIONS FOR HEPATITIS C IN MEDICARE POPULATION FROM 2013 TO 2020 Xiaohan Ying, Emily Smith, Rochelle Wong, Nicole Palmer, Russell Rosenblatt and Arun Jesudian, Weill Cornell Medicine, NY Background: Chronic hepatitis C (CHC) is a major cause of liver-related morbidity and mortality globally, and there are an estimated 2.4 million people in the United States living with CHC

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