This is where a medical weight loss program can play a crucial role
Wang Y, Ye J, Ganapathy V, Longo N: Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency
However, given the associated risks of cardiovascular disease and various cancers, the benefits of these medications, such as better glycemic control, weight loss and improvement in cardiometabolic risk factors as well as other obesity complications, appear to outweigh the risks for most adults with obesity [143, 153]
As far as clinical trials go, this is a pretty appalling number
The retatrutide mixing guide covers the details
I'll add that to my list of things to do in January when it's like, cold and depressing outside