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Conclusions Ischemic stroke triggers a coordinated metabolic crisis characterized by ATP depletion, mitochondrial dysfunction, excitotoxicity, oxidative and nitrosative stress, maladaptive glycolysis, lactate and pH dysregulation, NAD + /FAD imbalance, inflammatory immunometabolism, endothelial-pericyte uncoupling, and impaired neurovascular repair

Without sufficient B12, your body is unable to support its red blood cell growth

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doi:10.1016/S0002-9378(98)70645-3

This results in the various features of scurvy including capillary fragility manifested as hemorrhagic processes, delayed wound healing, and bony abnormalities