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A systematic review of GSH as an adjuvant therapy in Parkinson's disease identified one controlled trial 65 showing doubtful benefit

Mild GI changes Community sources describe occasional loose stool or transient appetite shifts in the first 1-2 weeks of use, sometimes attributed to systemic anti-inflammatory effects rather than direct GI irritation

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Theoretical interactions could occur with medications affecting blood clotting, immune function, or tissue growth

Ecotoxicol Environ Saf 157:255265

Additionally, it has been shown to stimulate collagen production, positively impacting skin elasticity and appearance