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T2D remission was reported in a low number of RCTs ( n = 5), and, therefore, we performed traditional meta-analyses for semaglutide only, and we showed the estimates of the other three studies in the same figures for convenience (that is, naltrexone plus bupropion, liraglutide, semaglutide and tirzepatide

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Most patients were middle-aged (with an average age of approximately 56 years) and overweight or with obesity (with an average BMI of approximately 32 kg/m 2 )