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The result is greater weight loss than single-action GLP-1 drugs in clinical trials the SURMOUNT-1 trial reported average weight loss of 22.5% over 72 weeks at the 15 mg dose, compared to roughly 15% for semaglutides STEP-1 trial
Serious side effects are rare when peptides are dosed correctly and sourced from licensed compounding pharmacies
However, it does carry risks
Oligomeric -syn interacts with cellular membranes to accelerate lipid peroxidation and integrates into the cytomembrane, leading to calcium influx, elevated intracellular calcium levels, and subsequent excitotoxicity and ferroptotic cell death (25)
Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1
Diabetes (2011) 60(4):124657
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