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Binding of OxLDL to LOX-1 promotes the production of O - and H 2 O 2 , as well as activation of NF-kB via p38 MAP kinase signaling pathway [178, 179], thus eliciting an inflammation in the endothelial cells
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BPC-157: 250500 mcg daily
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The trial was conducted across 17 sites in the USA and included 92 adults with type 2 diabetes and a BMI of 27 kg/m2 or higher on metformin with or without an SGLT2 inhibitor
doi: Walker E, Lo K, Tham S, et al
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