doi: 10.1371/journal.pone.0183680 145 AkazawaYCazanaveSMottJLElmiNBronkSFKohnoSet al
Key Points Oral semaglutide (Rybelsus) and injectable semaglutide (Ozempic, Wegovy) contain the same active ingredient but are administered differently Both forms yield similar results for both blood sugar control and weight loss, but higher doses produce more dramatic results Determining the right form for you depends on personal preferences, lifestyle, and specific health goals Are you trying to decide between taking a pill or using injectables for your diabetes or weight management
~50% of adults and 20% of children in China are obese, driven by rising obesity rates and Western-style dietary shifts
SURMOUNT-1: Tirzepatide 15 mg, the generational leap of 2022 SURMOUNT-1 (Jastreboff et al., NEJM 2022, PMID 35658024) randomized 2,539 obese adults without diabetes to tirzepatide 5, 10, or 15 mg/week or placebo over 72 weeks
Roughly 7 to 14 percent of people on retatrutide or semaglutide discontinue the drug due to side effects, versus just 2 percent on placebo
In the months since we launched the GLP-1 Supply Tracker, theres been ongoing news and updates about the GLP-1 shortages