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Human clinical evidence for TB-500 (a synthetic form of thymosin beta-4) is limited because most peer-reviewed studies involve the native peptide thymosin beta-4 in wound-healing settings rather than TB-500 specifically, but research does show its regenerative and anti-inflammatory effects in humans

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In vivo animal experiments showed that daily administration of NNMTi for 28 days to dietinduced obese (DIO) mice significantly upregulated the expression of lipolysisrelated genes (such as ATGL and HSL) and downregulated lipogenesisrelated genes (such as FAS and ACC), indicating that NNMTi effectively promotes fat breakdown and inhibits fat synthesis

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10.1007/s00415-009-5357-2 69 SchaefferE.RoebenB.GranertO.HanertA.Liepelt-ScarfoneI.LeksE.et al (2022)